HDL Metabolism
Posted By on September 30, 2020
Critical examination of the effectiveness of individual plant extracts on lipid metabolism and the prevention potential in atherosclerosis. All metabolism of lipids known as lipid metabolism, which includes admission to the body, the different uses of various lipids and the excrements of different metabolic end-products. Lipids serve the human body primarily for storing energy, membrane modules or to the “padding” of various organs. In contrast to the central role of the glucose, there are no cells that are necessarily dependent on lipids as an energy supplier. They serve primarily the reserve and only very few cells as primary care. Diseases of the cardio vascular system are among the leading causes of death in industrialized countries.
The trend is rising. Only in the Switzerland is fortunately decreasing in the last few years the tendency (BFS Switzerland). The main risk factor for cardiovascular disease are obesity, hypertension, diabetes mellitus and Dyslipoproteinamien. Atherosclerosis is the main cause of heart attack and stroke. Preliminary information in the treatment or prophylaxis of atherosclerosis is placed on two pillars: the so-called “lifestyle modification”. The goal is a significant reduction of triglyceride levels and the total cholesterol levels, as well as a redistribution of cholesterol fractions HDL cholesterol and at the expense of LDL cholesterol. By the Working Group “Lipids and arteriosclerosis” of the “Swiss society of Cardiology” a value for the total cholesterol is called target size of < 5.0 mmol/l specified. The German society for combating the lipid metabolism disorder and their sequelae “Research (lipid-Liga e.V.)” explains the following values as ‘normal’: total cholesterol < 200 mg / dl, which is equivalent to 5.2 mmol/l triglyceride < 200 mg / dl, which is equivalent to 2.3 mmol/l ratio of LDL / HDL cholesterol < 3, in the absence of other risk factors < 4 be no positive family history of coronary heart disease in the drug treatment of Dyslipoproteinemia in addition to HMG-CoA reductase, ion exchange resins, Nicotinic Acid, Fibrates, beta-sitosterol and cholesterol Resorptionshemmern (Ezetimibe) also herbal supplements used for a positive effect on the lipid metabolism and a prophylaxis of atherosclerosis are postulated.
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